MS-FLAG, a Novel Real-Time Signal Generation Method for Methylation-Specific PCR
نویسندگان
چکیده
منابع مشابه
MS-FLAG, a novel real-time signal generation method for methylation-specific PCR.
BACKGROUND Aberrant promoter methylation is a major mechanism for silencing tumor suppressor genes in cancer. Detection of hypermethylation is used as a molecular marker for early cancer diagnosis, as a prognostic index, or to define therapeutic targets for reversion of aberrant methylation. We report on a novel signal generation technology for real-time PCR to detect gene promoter methylation....
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2007
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2007.094011